New Synthetic Antioxidant Inspired by ‘Conan the Bacterium’ Could Shield Humans from Radiation

New analysis has drawn inspiration from Deinococcus radiodurans, a bacterium able to withstanding excessive radiation ranges, to create a possible antioxidant which will defend people from ionising radiation. Known as “Conan the Bacterium,” this microbe has been studied for its extraordinary resistance to radiation doses far past what people can endure. In a examine printed on December 12, 2024, in Proceedings of the National Academy of Sciences (PNAS), scientists examined how the bacterium survives circumstances that usually harm DNA, proteins, and cells. According to experiences, the resilience of D. radiodurans is attributed to its sturdy cell wall, extremely environment friendly DNA restore mechanisms, and antioxidants that neutralise dangerous free radicals.

Unique Antioxidant Complex Developed

Researchers led by Michael Daly, a geneticist on the Uniformed Services University in Maryland, developed an artificial antioxidant impressed by the bacterium’s protecting mechanisms. Speaking to Live Science, Daly explained that publicity to ionising radiation — similar to gamma rays and cosmic radiation — poses dangers to each micro organism and people, doubtlessly inflicting DNA harm, protein oxidation, and extreme well being circumstances.

The workforce created a lab-made antioxidant advanced known as manganese-dependent peptide (MDP). This was designed by combining manganese ions, phosphate ions, and a peptide modelled on the amino acids present in D. radiodurans. Co-author Brian Hoffman, a chemistry professor at Northwestern University, acknowledged that the interplay between the parts created a strong protecting compound, able to withstanding radiation ranges over 12,000 instances larger than the deadly dose for people.

Potential Applications for Space and Medicine

The antioxidant has sparked curiosity for area exploration and well being care. Daly famous that astronauts on missions to Mars, the place publicity to cosmic radiation is extended, may gain advantage from this cost-effective and non-toxic radioprotector. On Earth, it’s prompt that MDP may assist handle acute radiation syndrome and even fight metabolic ageing, though additional research are wanted to make sure its security and efficacy for human use. Reportedly, the researchers proceed to refine the construction of MDP, aiming to boost its properties for broader functions.