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A lethal bacterial an infection is spreading in Japan. Here’s what to find out about causes and prevention.

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A probably lethal bacterial an infection referred to as streptococcal poisonous shock syndrome, or STSS, is spreading in Japan, prompting questions on what causes it and find out how to stop it. 

Japan’s National Institute of Infectious Diseases issued a statement in March warning that STSS was rising within the nation. As of June 2, Japan’s well being ministry stories 977 cases because the begin of 2024 — surpassing last year’s 941 cases.

That’s virtually two and a half instances the quantity reported within the U.S. up to now this yr.

STSS is a “rare, but serious” bacterial infection that may “develop in a short time right into a life-threatening emergency,” based on the Centers for Disease Control and Prevention.

First signs of STSS typically embrace fever, chills, muscle aches, nausea and vomiting, the CDC states. Japan’s well being ministry provides individuals additionally expertise ache and swelling within the legs and arms.

After 24 to 48 hours, low blood strain sometimes develops and might trigger extra severe points, together with organ failure, elevated coronary heart price and fast respiration. 

“Even with therapy, STSS may be lethal. Out of 10 individuals with STSS, as many as 3 individuals will die from the an infection,” the CDC says.

In the U.S., the CDC has tallied 395 cases reported up to now this yr, not far off from the 390 reported right now final yr.

What causes streptococcal poisonous shock syndrome?

STSS is attributable to toxins launched by Streptococcus pyogenes, often known as Group A Streptococcus, or GAS, which generally trigger sore throat and pores and skin infections, explains Dr. Céline Gounder, a CBS News medical contributor, infectious illnesses skilled and editor-at-large for public well being at KFF Health News.

“Less generally, GAS causes an infection within the blood, lungs, in addition to ‘flesh-eating’ infections,” Gounder defined. “Approximately 30 to 60% of individuals experiencing these most severe infections will die from them.”

It just isn’t but understood why these extreme infections have gotten extra widespread, specialists say, however there are methods to assist stop an infection.

“Because chickenpox and influenza are threat elements for extreme GAS an infection, vaccination towards varicella zoster virus and influenza can scale back the danger of extreme GAS an infection,” Gounder stated. “People who’ve been in shut contact with somebody with extreme GAS infections and who’re immunocompromised, pregnant, or have open wounds must be given antibiotics to stop an infection.”

Where is SSTS discovered?

Anyone can get STSS, the CDC says, however sure threat elements can enhance your threat, together with:

  • Age — it is commonest in adults 65 or older
  • Infections or accidents that break the pores and skin
  • Other well being elements, together with diabetes and alcohol use dysfunction

Risk elements for extreme Group A Streptococcus infections, Gounder stated, embrace trauma, surgical procedure, burns, immunosuppression, being pregnant, diabetes, injection drug use, homelessness, and chickenpox or influenza an infection.

Since late 2022, a number of international locations have skilled rising charges of GAS, together with the United Kingdom, Ireland, France, the Netherlands and Sweden.

“Outbreaks like these communicate to the necessity for ongoing infectious illness surveillance and management, not solely within the United States, however all over the world,” Gounder stated. 



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